TolaSure’s primary activity is to accelerate epithelialization for rapid wound closure by stimulating growth factors, producing hydrogen peroxide and oxygen to promote healing. TolaSure is formulated as a time release gel, into sterile & shelf stable 1mL applicator bottles for an easy to use product. When compared to similar products TolaSure outperforms traditional bandages, hydrogels, creams, growth factors and bio-active nanoparticles. In addition to accelerating all phases of wound healing, TolaSure exerts broad spectrum antimicrobial (i.e. antiviral, anti-bacterial and anti-fungal) activity during wound healing. TolaSure’s unique formulation allows it to be applied to dry or moist skin. In a seeping or infected wound TolaSure is allowed to dry creating a protective wound film. In a dry wound it can be applied and covered with a traditional bandage to prevent evaporation and keep the wound moist. BioMendics is also incorporating TolaSure technology into an alginate based dressing to provide additional product alternatives.
Please read more about the wound healing process and how TolaSure heals wounds by targeting all phases of the healing process
The Wound Healing process is further illustrated below:
All wounds start with a breach in the skin (Injury) that may be done deliberately in the case of a surgical wound or accidentally in the cases of cuts, scrapes, lacerations and burns. Wounds may also occur in individuals who are bed ridden or suffer from a chronic disease such as diabetes. A loss of skin integrity results in bleeding which must be stopped by the body's own blood clotting mechanism. Once the bleeding is controlled, the wound enters the inflammation phase where the tissue swells and inflammatory markers secreted by the injured and surrounding cells help recruit immune cells to the site of injury. After this stage is complete, the skin enters the proliferative phase where the keratinocytes and fibroblast start to multiply and migrate to replace the missing tissue. Following wound closure, the risk of infection has been reduced and the skin enters the remodeling phase to reestablish all the connective tissue, blood vessels, hair follicles and glands returning the skin to full strength.
In the case of a chronic or non-healing wound the wound remains in the inflammation stage of the healing process.